Diffuse large B-cell lymphomas have spatially defined, tumor immune microenvironments revealed by high-parameter imaging

Wright, K.
2023
Diffuse large B-cell lymphoma (DLBCL) not otherwise specified is the most common aggressive non-Hodgkin lymphoma and a biologically heterogeneous disease. Despite the development of effective

Codetection of DNA, RNA transcripts, and protein epitopes on the same SIV infected tissue section using PANINI

Jiang, S. et. al.
Understanding the mechanisms of HIV tissue persistence necessitates the ability to visualize tissue microenvironments where infected cells reside; however, technological barriers limit our ability to

Development of a spatial high-plex panel for Ebola viral-host interactions in non-human primates

Jiang Sizun
2021
A 21-marker CODEX panel for Ebola virus (EBOV) infection in rhesus macaques during, allowing the interrogation of the spatial immune microenvironment in response to the

Spatial dissection of Host-Microbiome interactions within the Colitis TME

Zhu, B.
2024
The intricate and dynamic interactions between the host immune system and its microbiome constituents undergo dynamic shifts in response to perturbations to the intestinal tissue

Immune-epithelial dynamics in Chronically inflamed Nasal Epithelium

Liao, G.
2023
Chronic rhinosinusitis (CRS) is a common inflammatory disease of the sinonasal cavity that affects millions of individuals worldwide. The complex pathophysiology of CRS remains poorly

Understanding the CTCL TME for Effective Immunotherapies

Phillips, D. et. al.
2021
"Immunotherapies are transforming cancer treatment by harnessing the power of the immune system. Beyond traditional checkpoint inhibitors like CTLA-4, PD-1, and PD-L1, new therapies targeting

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Uncovering immunosuppressive mechanisms in EBV+ cHL patients using Elucidate Bio’s Spatial Profiling pipeline